Serendipitous Discovery of a Guanine-rich DNA Molecule with a Highly Stable Structure in Urea

We have made an accidental discovery of an unusual, single-stranded, guanine-rich DNA molecule that is capable of adopting a folded structure in 7 M urea (7MU) known to denature nucleic acid structures. The folding of this molecule requires Na(+) and Mg(2+) and the folded structure remains stable wh...

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Detalles Bibliográficos
Autores principales: Zhang, Wenqing, Liu, Meng, Lee, Christine, Salena, Bruno J., Li, Yingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792554/
https://www.ncbi.nlm.nih.gov/pubmed/29386529
http://dx.doi.org/10.1038/s41598-018-20248-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792554/
https://www.ncbi.nlm.nih.gov/pubmed/29386529
http://dx.doi.org/10.1038/s41598-018-20248-w

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