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Serendipitous Discovery of a Guanine-rich DNA Molecule with a Highly Stable Structure in Urea
We have made an accidental discovery of an unusual, single-stranded, guanine-rich DNA molecule that is capable of adopting a folded structure in 7 M urea (7MU) known to denature nucleic acid structures. The folding of this molecule requires Na(+) and Mg(2+) and the folded structure remains stable wh...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792554/ https://www.ncbi.nlm.nih.gov/pubmed/29386529 http://dx.doi.org/10.1038/s41598-018-20248-w |