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Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro
Development of in vitro culture systems for the generation of red blood cells is a goal of scientists globally with the aim of producing clinical grade products for transfusion. Although mature reticulocytes can be efficiently generated by such systems, the numbers produced fall short of that requir...
Autores principales: | Trakarnsanga, Kongtana, Wilson, Marieangela C., Heesom, Kate J., Andrienko, Tatyana N., Srisawat, Chatchawan, Frayne, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792592/ https://www.ncbi.nlm.nih.gov/pubmed/29386568 http://dx.doi.org/10.1038/s41598-018-20491-1 |
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