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Differences in the mechanical unfolding pathways of apo- and copper-bound azurins

Metalloproteins carry out diverse biological functions including metal transport, electron transfer, and catalysis. At present, the influence of metal cofactors on metalloprotein stability is not well understood. Here, we report the mechanical stability and unfolding pathway of azurin, a cupredoxin...

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Detalles Bibliográficos
Autores principales: Yadav, Anju, Paul, Sanjoy, Venkatramani, Ravindra, Ainavarapu, Sri Rama Koti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792602/
https://www.ncbi.nlm.nih.gov/pubmed/29386517
http://dx.doi.org/10.1038/s41598-018-19755-7