Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics

Plasmid-borne colistin resistance mediated by mcr-1 may contribute to the dissemination of pan-resistant Gram-negative bacteria. Here, we show that mcr-1 confers resistance to colistin-induced lysis and bacterial cell death, but provides minimal protection from the ability of colistin to disrupt the...

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Detalles Bibliográficos
Autores principales: MacNair, Craig R., Stokes, Jonathan M., Carfrae, Lindsey A., Fiebig-Comyn, Aline A., Coombes, Brian K., Mulvey, Michael R., Brown, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792607/
https://www.ncbi.nlm.nih.gov/pubmed/29386620
http://dx.doi.org/10.1038/s41467-018-02875-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792607/
https://www.ncbi.nlm.nih.gov/pubmed/29386620
http://dx.doi.org/10.1038/s41467-018-02875-z

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