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Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
Metastasis is the leading cause of death in patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonisation are poorly understood. Here, we deploy comparative genomics to identify and validate clinically relevant drivers of melanoma metastasis. To do...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792739/ https://www.ncbi.nlm.nih.gov/pubmed/29193607 http://dx.doi.org/10.1002/1878-0261.12161 |