Cargando…

Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis

Metastasis is the leading cause of death in patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonisation are poorly understood. Here, we deploy comparative genomics to identify and validate clinically relevant drivers of melanoma metastasis. To do...

Descripción completa

Detalles Bibliográficos
Autores principales: Del Castillo Velasco‐Herrera, Martin, van der Weyden, Louise, Nsengimana, Jeremie, Speak, Anneliese O., Sjöberg, Marcela K., Bishop, David Timothy, Jönsson, Göran, Newton‐Bishop, Julia, Adams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792739/
https://www.ncbi.nlm.nih.gov/pubmed/29193607
http://dx.doi.org/10.1002/1878-0261.12161