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TCF21 hypermethylation regulates renal tumor cell clonogenic proliferation and migration

We recently identified hypermethylation at the gene promoter of transcription factor 21 (TCF21) in clear cell sarcoma of the kidney (CCSK), a rare pediatric renal tumor. TCF21 is a transcription factor involved in tubular epithelial development of the kidney and is a candidate tumor suppressor. As t...

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Detalles Bibliográficos
Autores principales: Gooskens, Saskia L., Klasson, Timothy D., Gremmels, Hendrik, Logister, Ive, Pieters, Robert, Perlman, Elizabeth J., Giles, Rachel H., van den Heuvel‐Eibrink, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792742/
https://www.ncbi.nlm.nih.gov/pubmed/29080283
http://dx.doi.org/10.1002/1878-0261.12149