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Isoaaptamine Induces T-47D Cells Apoptosis and Autophagy via Oxidative Stress

Aaptos is a genus of marine sponge which belongs to Suberitidae and is distributed in tropical and subtropical oceans. Bioactivity-guided fractionation of Aaptos sp. methanolic extract resulted in the isolation of aaptamine, demethyloxyaaptamine, and isoaaptamine. The cytotoxic activity of the isola...

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Detalles Bibliográficos
Autores principales: Wu, Chih-Fung, Lee, Man-Gang, El-Shazly, Mohamed, Lai, Kuei-Hung, Ke, Seng-Chung, Su, Chiang-Wen, Shih, Shou-Ping, Sung, Ping-Jyun, Hong, Ming-Chang, Wen, Zhi-Hong, Lu, Mei-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793066/
https://www.ncbi.nlm.nih.gov/pubmed/29315210
http://dx.doi.org/10.3390/md16010018