The Bioactive Extract of Pinnigorgia sp. Induces Apoptosis of Hepatic Stellate Cells via ROS-ERK/JNK-Caspase-3 Signaling

The activation of hepatic stellate cells (HSCs) is a significant phenomenon during the pathogenesis of liver disorders, including liver cirrhosis and fibrosis. Here, we identified that the extract from a gorgonian coral Pinnigorgia sp. (Pin) induced apoptosis of HSC-T6 cells. Pin inhibited the viabi...

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Detalles Bibliográficos
Autores principales: Kuo, Liang-Mou, Chen, Po-Jen, Sung, Ping-Jyun, Chang, Yu-Chia, Ho, Chun-Ting, Wu, Yi-Hsiu, Hwang, Tsong-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793067/
https://www.ncbi.nlm.nih.gov/pubmed/29315209
http://dx.doi.org/10.3390/md16010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793067/
https://www.ncbi.nlm.nih.gov/pubmed/29315209
http://dx.doi.org/10.3390/md16010019

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