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High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein

The protein toxin Cytotoxic Necrotizing Factor 1 (CNF1) is a major virulence factor of pathogenic Escherichia coli strains. It belongs to a family of single chain AB-toxins, which enter mammalian cells by receptor-mediated endocytosis. Recently, we identified the Lutheran (Lu) adhesion glycoprotein/...

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Detalles Bibliográficos
Autores principales: Reppin, Franziska, Cochet, Sylvie, El Nemer, Wassim, Fritz, Günter, Schmidt, Gudula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793090/
https://www.ncbi.nlm.nih.gov/pubmed/29267242
http://dx.doi.org/10.3390/toxins10010003