Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies

Diphtheria toxin (DT) related targeted toxins are effective in cancer treatment, but efficacy diminishes in time because of their immunogenic potential and/or former vaccinations. In order to overcome this limitation for DT2219, a promising bispecific targeted toxin which targets CD19 and CD22, we d...

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Detalles Bibliográficos
Autores principales: Schmohl, Joerg U., Todhunter, Deborah, Taras, Elizabeth, Bachanova, Veronika, Vallera, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793119/
https://www.ncbi.nlm.nih.gov/pubmed/29316610
http://dx.doi.org/10.3390/toxins10010032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793119/
https://www.ncbi.nlm.nih.gov/pubmed/29316610
http://dx.doi.org/10.3390/toxins10010032

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