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Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies
Diphtheria toxin (DT) related targeted toxins are effective in cancer treatment, but efficacy diminishes in time because of their immunogenic potential and/or former vaccinations. In order to overcome this limitation for DT2219, a promising bispecific targeted toxin which targets CD19 and CD22, we d...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793119/ https://www.ncbi.nlm.nih.gov/pubmed/29316610 http://dx.doi.org/10.3390/toxins10010032 |