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PGC1α: Friend or Foe in Cancer?

The PGC1 family (Peroxisome proliferator-activated receptor γ (PPARγ) coactivators) of transcriptional coactivators are considered master regulators of mitochondrial biogenesis and function. The PGC1α isoform is expressed especially in metabolically active tissues, such as the liver, kidneys and bra...

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Detalles Bibliográficos
Autores principales: Mastropasqua, Francesca, Girolimetti, Giulia, Shoshan, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793199/
https://www.ncbi.nlm.nih.gov/pubmed/29361779
http://dx.doi.org/10.3390/genes9010048