Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

BACKGROUND: Accumulating evidence indicates that Tau pathology can spread from neuron to neuron by intake and coaggregation of the hyperphosphorylated Tau (p-Tau) seeds with the host neuron protein. Thus, clearance of Tau seeds by immunization with Tau antibodies could provide a potential therapeuti...

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Detalles Bibliográficos
Autores principales: Dai, Chun-ling, Hu, Wen, Tung, Yunn Chyn, Liu, Fei, Gong, Cheng-Xin, Iqbal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793372/
https://www.ncbi.nlm.nih.gov/pubmed/29386065
http://dx.doi.org/10.1186/s13195-018-0341-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793372/
https://www.ncbi.nlm.nih.gov/pubmed/29386065
http://dx.doi.org/10.1186/s13195-018-0341-7

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