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Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability

BACKGROUND: The tumour microenvironment is essential for cancer progress and metastasis. Integrin-β5 (ITGB5), a member of the integrin family, has been implicated to mediate the interactions of cells with the extracellular matrix (ECM) and promote tumorigenesis in several malignancies. However, the...

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Detalles Bibliográficos
Autores principales: Lin, Zhikun, He, Ruiping, Luo, Haifeng, Lu, Chang, Ning, Zhen, Wu, Yuanhang, Han, Chuanchun, Tan, Guang, Wang, Zhongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793391/
https://www.ncbi.nlm.nih.gov/pubmed/29386044
http://dx.doi.org/10.1186/s13046-018-0691-9