Germline contamination and leakage in whole genome somatic single nucleotide variant detection

BACKGROUND: The clinical sequencing of cancer genomes to personalize therapy is becoming routine across the world. However, concerns over patient re-identification from these data lead to questions about how tightly access should be controlled. It is not thought to be possible to re-identify patient...

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Detalles Bibliográficos
Autores principales: Sendorek, Dorota H., Caloian, Cristian, Ellrott, Kyle, Bare, J. Christopher, Yamaguchi, Takafumi N., Ewing, Adam D., Houlahan, Kathleen E., Norman, Thea C., Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793408/
https://www.ncbi.nlm.nih.gov/pubmed/29385983
http://dx.doi.org/10.1186/s12859-018-2046-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793408/
https://www.ncbi.nlm.nih.gov/pubmed/29385983
http://dx.doi.org/10.1186/s12859-018-2046-0

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