Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model

BACKGROUND: In bone tissue engineering (BTE), extensive research into vascular endothelial growth factor A (VEGFA)-mediated angiogenesis has yielded inconsistent results. The aim of this study was to investigate the influence on angio- and osteogenesis of adenoviral-mediated delivery of VEGFA alone...

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Detalles Bibliográficos
Autores principales: Sharma, Sunita, Sapkota, Dipak, Xue, Ying, Rajthala, Saroj, Yassin, Mohammed A., Finne-Wistrand, Anna, Mustafa, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793460/
https://www.ncbi.nlm.nih.gov/pubmed/29386057
http://dx.doi.org/10.1186/s13287-018-0778-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793460/
https://www.ncbi.nlm.nih.gov/pubmed/29386057
http://dx.doi.org/10.1186/s13287-018-0778-4

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