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Functional implications of corticosteroid-binding globulin N-glycosylation

Corticosteroid-binding globulin (CBG) is a plasma carrier of glucocorticoids. Human and rat CBGs have six N-glycosylation sites. Glycosylation of human CBG influences its steroid-binding activity, and there are N-glycosylation sites in the reactive center loops (RCLs) of human and rat CBGs. Proteoly...

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Detalles Bibliográficos
Autores principales: Simard, Marc, Underhill, Caroline, Hammond, Geoffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793714/
https://www.ncbi.nlm.nih.gov/pubmed/29273683
http://dx.doi.org/10.1530/JME-17-0234