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Exploring background mutational processes to decipher cancer genetic heterogeneity

Much remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A growing body of evidence supports mutation rate dependence on the local DNA sequence context for various types of mutations. We propose several too...

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Detalles Bibliográficos
Autores principales: Goncearenco, Alexander, Rager, Stephanie L., Li, Minghui, Sang, Qing-Xiang, Rogozin, Igor B., Panchenko, Anna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793731/
https://www.ncbi.nlm.nih.gov/pubmed/28472504
http://dx.doi.org/10.1093/nar/gkx367