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Exploring background mutational processes to decipher cancer genetic heterogeneity
Much remains unknown about the progression and heterogeneity of mutational processes in different cancers and their diagnostic and clinical potential. A growing body of evidence supports mutation rate dependence on the local DNA sequence context for various types of mutations. We propose several too...
Autores principales: | Goncearenco, Alexander, Rager, Stephanie L., Li, Minghui, Sang, Qing-Xiang, Rogozin, Igor B., Panchenko, Anna R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793731/ https://www.ncbi.nlm.nih.gov/pubmed/28472504 http://dx.doi.org/10.1093/nar/gkx367 |
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