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Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing

Pancreatic neuroendocrine tumors (PNETs) are a genomically and clinically heterogeneous group of pancreatic neoplasms often diagnosed with distant metastases. Recurrent somatic mutations, chromosomal aberrations, and gene expression signatures in PNETs have been described, but the clinical significa...

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Detalles Bibliográficos
Autores principales: Wong, Hui-li, Yang, Kevin C., Shen, Yaoqing, Zhao, Eric Y., Loree, Jonathan M., Kennecke, Hagen F., Kalloger, Steve E., Karasinska, Joanna M., Lim, Howard J., Mungall, Andrew J., Feng, Xiaolan, Davies, Janine M., Schrader, Kasmintan, Zhou, Chen, Karsan, Aly, Jones, Steven J.M., Laskin, Janessa, Marra, Marco A., Schaeffer, David F., Gorski, Sharon M., Renouf, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793777/
https://www.ncbi.nlm.nih.gov/pubmed/29092957
http://dx.doi.org/10.1101/mcs.a002329