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Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis

Noncoding transcription is a defining feature of active enhancers, linking transcription factor (TF) binding to the molecular mechanisms controlling gene expression. To determine the relationship between enhancer activity and biological outcomes in breast cancers, we profiled the transcriptomes (usi...

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Detalles Bibliográficos
Autores principales: Franco, Hector L., Nagari, Anusha, Malladi, Venkat S., Li, Wenqian, Xi, Yuanxin, Richardson, Dana, Allton, Kendra L., Tanaka, Kaori, Li, Jing, Murakami, Shino, Keyomarsi, Khandan, Bedford, Mark T., Shi, Xiaobing, Li, Wei, Barton, Michelle C., Dent, Sharon Y.R., Kraus, W. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793780/
https://www.ncbi.nlm.nih.gov/pubmed/29273624
http://dx.doi.org/10.1101/gr.226019.117