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Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis
Noncoding transcription is a defining feature of active enhancers, linking transcription factor (TF) binding to the molecular mechanisms controlling gene expression. To determine the relationship between enhancer activity and biological outcomes in breast cancers, we profiled the transcriptomes (usi...
Autores principales: | Franco, Hector L., Nagari, Anusha, Malladi, Venkat S., Li, Wenqian, Xi, Yuanxin, Richardson, Dana, Allton, Kendra L., Tanaka, Kaori, Li, Jing, Murakami, Shino, Keyomarsi, Khandan, Bedford, Mark T., Shi, Xiaobing, Li, Wei, Barton, Michelle C., Dent, Sharon Y.R., Kraus, W. Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793780/ https://www.ncbi.nlm.nih.gov/pubmed/29273624 http://dx.doi.org/10.1101/gr.226019.117 |
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