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Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast

The functional consequences of alternative splicing on altering the transcription rate have been the subject of intensive study in mammalian cells but less is known about effects of splicing on changing the transcription rate in yeast. We present several lines of evidence showing that slow RNA polym...

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Detalles Bibliográficos
Autores principales: Aslanzadeh, Vahid, Huang, Yuanhua, Sanguinetti, Guido, Beggs, Jean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793784/
https://www.ncbi.nlm.nih.gov/pubmed/29254943
http://dx.doi.org/10.1101/gr.225615.117