Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

Understanding transcriptome complexity is crucial for understanding human biology and disease. Technologies such as Synthetic long-read RNA sequencing (SLR-RNA-seq) delivered 5 million isoforms and allowed assessing splicing coordination. Pacific Biosciences and Oxford Nanopore increase throughput a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tilgner, Hagen, Jahanbani, Fereshteh, Gupta, Ishaan, Collier, Paul, Wei, Eric, Rasmussen, Morten, Snyder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793787/
https://www.ncbi.nlm.nih.gov/pubmed/29196558
http://dx.doi.org/10.1101/gr.230516.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793787/
https://www.ncbi.nlm.nih.gov/pubmed/29196558
http://dx.doi.org/10.1101/gr.230516.117

Ejemplares similares