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Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

Understanding transcriptome complexity is crucial for understanding human biology and disease. Technologies such as Synthetic long-read RNA sequencing (SLR-RNA-seq) delivered 5 million isoforms and allowed assessing splicing coordination. Pacific Biosciences and Oxford Nanopore increase throughput a...

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Detalles Bibliográficos
Autores principales:	Tilgner, Hagen, Jahanbani, Fereshteh, Gupta, Ishaan, Collier, Paul, Wei, Eric, Rasmussen, Morten, Snyder, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793787/ https://www.ncbi.nlm.nih.gov/pubmed/29196558 http://dx.doi.org/10.1101/gr.230516.117

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