Detecting differential copy number variation between groups of samples

We present a method to detect copy number variants (CNVs) that are differentially present between two groups of sequenced samples. We use a finite-state transducer where the emitted read depth is conditioned on the mappability and GC-content of all reads that occur at a given base position. In this...

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Detalles Bibliográficos
Autores principales: Lowe, Craig B., Sanchez-Luege, Nicelio, Howes, Timothy R., Brady, Shannon D., Daugherty, Rhea R., Jones, Felicity C., Bell, Michael A., Kingsley, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793789/
https://www.ncbi.nlm.nih.gov/pubmed/29229672
http://dx.doi.org/10.1101/gr.206938.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793789/
https://www.ncbi.nlm.nih.gov/pubmed/29229672
http://dx.doi.org/10.1101/gr.206938.116

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