Functional Defects From Endocrine Disease–Associated Mutations in HLXB9 and Its Interacting Partner, NONO

The insulin-secreting pancreatic neuroendocrine tumors, insulinomas, characterized by increased pancreatic islet β-cell proliferation, express the phosphorylated isoform of the β-cell differentiation factor HLXB9 that interacts with NONO/p54(NRB), a survival factor. Interestingly, two different homo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kharade, Sampada S., Parekh, Vaishali I., Agarwal, Sunita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793795/
https://www.ncbi.nlm.nih.gov/pubmed/29309627
http://dx.doi.org/10.1210/en.2017-03155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793795/
https://www.ncbi.nlm.nih.gov/pubmed/29309627
http://dx.doi.org/10.1210/en.2017-03155

Ejemplares similares