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Functional Defects From Endocrine Disease–Associated Mutations in HLXB9 and Its Interacting Partner, NONO
The insulin-secreting pancreatic neuroendocrine tumors, insulinomas, characterized by increased pancreatic islet β-cell proliferation, express the phosphorylated isoform of the β-cell differentiation factor HLXB9 that interacts with NONO/p54(NRB), a survival factor. Interestingly, two different homo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793795/ https://www.ncbi.nlm.nih.gov/pubmed/29309627 http://dx.doi.org/10.1210/en.2017-03155 |