Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTPases regulate mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein motors. By generating Miro1/2 double‐knockout mouse embryos and single‐ and double‐knockout embryonic fibroblasts, we demon...

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Detalles Bibliográficos
Autores principales: López‐Doménech, Guillermo, Covill‐Cooke, Christian, Ivankovic, Davor, Halff, Els F, Sheehan, David F, Norkett, Rosalind, Birsa, Nicol, Kittler, Josef T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793800/
https://www.ncbi.nlm.nih.gov/pubmed/29311115
http://dx.doi.org/10.15252/embj.201696380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793800/
https://www.ncbi.nlm.nih.gov/pubmed/29311115
http://dx.doi.org/10.15252/embj.201696380

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