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ThreaDomEx: a unified platform for predicting continuous and discontinuous protein domains by multiple-threading and segment assembly

We develop a hierarchical pipeline, ThreaDomEx, for both continuous domain (CD) and discontinuous domain (DCD) structure predictions. Starting from a query sequence, ThreaDomEx first threads it through the PDB to identify multiple structure templates, where a profile of domain conservation score (DC...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Wang, Jian, Li, Ruiming, Shi, Qiang, Xue, Zhidong, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793814/
https://www.ncbi.nlm.nih.gov/pubmed/28498994
http://dx.doi.org/10.1093/nar/gkx410