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ThreaDomEx: a unified platform for predicting continuous and discontinuous protein domains by multiple-threading and segment assembly
We develop a hierarchical pipeline, ThreaDomEx, for both continuous domain (CD) and discontinuous domain (DCD) structure predictions. Starting from a query sequence, ThreaDomEx first threads it through the PDB to identify multiple structure templates, where a profile of domain conservation score (DC...
Autores principales: | Wang, Yan, Wang, Jian, Li, Ruiming, Shi, Qiang, Xue, Zhidong, Zhang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793814/ https://www.ncbi.nlm.nih.gov/pubmed/28498994 http://dx.doi.org/10.1093/nar/gkx410 |
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