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Linking autoimmunity to the origin of the adaptive immune system

In jawed vertebrates, the adaptive immune system (AIS) cooperates with the innate immune system (IIS) to protect hosts from infections. Although targeting non-self-components, the AIS also generates self-reactive antibodies which, when inadequately counter-selected, can give rise to autoimmune disea...

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Detalles Bibliográficos
Autores principales: Bayersdorf, Robert, Fruscalzo, Arrigo, Catania, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793817/
https://www.ncbi.nlm.nih.gov/pubmed/29423226
http://dx.doi.org/10.1093/emph/eoy001