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5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model

BACKGROUND: Previous reports suggest that 5-hydroxytryptamine might play a role in the antidepressant actions of (R,S)-ketamine. However, its role in the antidepressant actions of (R)-ketamine, which is more potent than (S)-ketamine, is unknown. This study was conducted to examine whether 5-hydroxyt...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Dong, Chao, Fujita, Yuko, Fujita, Atsuhiro, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793842/
https://www.ncbi.nlm.nih.gov/pubmed/29155989
http://dx.doi.org/10.1093/ijnp/pyx100