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Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer

Colorectal cancer (CRC) tends to occur at older age; however, CRC incidence rates have been rising sharply among young age groups. The increasing prevalence of obesity is recognized as a major risk, yet the mechanistic underpinnings remain poorly understood. Using a diet-induced obesity mouse model,...

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Detalles Bibliográficos
Autores principales: Li, Ruifang, Grimm, Sara A., Mav, Deepak, Gu, Haiwei, Djukovic, Danijel, Shah, Ruchir, Merrick, B. Alex, Raftery, Daniel, Wade, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793878/
https://www.ncbi.nlm.nih.gov/pubmed/29346762
http://dx.doi.org/10.1016/j.celrep.2017.12.071