Cargando…
Cytosolic Proteostasis via Importing of Misfolded Proteins into Mitochondria
Loss of proteostasis underlies aging and neurodegeneration characterized by the accumulation of protein aggregates and mitochondrial dysfunction(1–5). Although many neurodegenerative-disease proteins can be found in mitochondria(4,6), it remains unclear how these disease manifestations may be relate...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793917/ https://www.ncbi.nlm.nih.gov/pubmed/28241148 http://dx.doi.org/10.1038/nature21695 |