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Contributions of Noncanonical Smoothened Signaling During Embryonic Development

The Sonic Hedgehog (Shh) signaling pathway is active during embryonic development in metazoans, and provides instructional cues necessary for proper tissue patterning. The pathway signal transducing component, Smoothened (Smo), is a G protein-coupled receptor (GPCR) that has been demonstrated to sig...

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Detalles Bibliográficos
Autores principales: Pandit, Tanushree, Ogden, Stacey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794034/
https://www.ncbi.nlm.nih.gov/pubmed/29399514
http://dx.doi.org/10.3390/jdb5040011