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Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide
Staphylococcus aureus requires branched-chain amino acids (BCAAs; isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acid synthesis, and environmental adaptation by responding to their availability via the global transcriptional regulator CodY. The importance of BCAAs for S. au...
Autores principales: | Kaiser, Julienne C., King, Alyssa N., Grigg, Jason C., Sheldon, Jessica R., Edgell, David R., Murphy, Michael E. P., Brinsmade, Shaun R., Heinrichs, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794164/ https://www.ncbi.nlm.nih.gov/pubmed/29357354 http://dx.doi.org/10.1371/journal.pgen.1007159 |
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