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Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here, we tested the hypothesis that β- and γ-actin functions ar...

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Detalles Bibliográficos
Autores principales: Vedula, Pavan, Kurosaka, Satoshi, Leu, Nicolae Adrian, Wolf, Yuri I, Shabalina, Svetlana A, Wang, Junling, Sterling, Stephanie, Dong, Dawei W, Kashina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794254/
https://www.ncbi.nlm.nih.gov/pubmed/29244021
http://dx.doi.org/10.7554/eLife.31661