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The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

The ribbon is the structural hallmark of cochlear inner hair cell (IHC) afferent synapses, yet its role in information transfer to spiral ganglion neurons (SGNs) remains unclear. We investigated the ribbon’s contribution to IHC synapse formation and function using KO mice lacking RIBEYE. Despite los...

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Detalles Bibliográficos
Autores principales: Becker, Lars, Schnee, Michael E, Niwa, Mamiko, Sun, Willy, Maxeiner, Stephan, Talaei, Sara, Kachar, Bechara, Rutherford, Mark A, Ricci, Anthony J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794257/
https://www.ncbi.nlm.nih.gov/pubmed/29328021
http://dx.doi.org/10.7554/eLife.30241