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The synaptic ribbon is critical for sound encoding at high rates and with temporal precision

We studied the role of the synaptic ribbon for sound encoding at the synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in mice lacking RIBEYE (RBE(KO/KO)). Electron and immunofluorescence microscopy revealed a lack of synaptic ribbons and an assembly of several small active...

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Detalles Bibliográficos
Autores principales: Jean, Philippe, Lopez de la Morena, David, Michanski, Susann, Jaime Tobón, Lina María, Chakrabarti, Rituparna, Picher, Maria Magdalena, Neef, Jakob, Jung, SangYong, Gültas, Mehmet, Maxeiner, Stephan, Neef, Andreas, Wichmann, Carolin, Strenzke, Nicola, Grabner, Chad, Moser, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794258/
https://www.ncbi.nlm.nih.gov/pubmed/29328020
http://dx.doi.org/10.7554/eLife.29275