Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses

Since the invention of systematic evolution of ligands by exponential enrichment, many short oligonucleotides (or aptamers) have been reported that can bind to a wide range of target molecules with high affinity and specificity. Previously, we reported an RNA aptamer that shows high affinity to the...

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Detalles Bibliográficos
Autores principales: Takada, Kenta, Amano, Ryo, Nomura, Yusuke, Tanaka, Yoichiro, Sugiyama, Shigeru, Nagata, Takashi, Katahira, Masato, Nakamura, Yoshikazu, Kozu, Tomoko, Sakamoto, Taiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794459/
https://www.ncbi.nlm.nih.gov/pubmed/29435416
http://dx.doi.org/10.1002/2211-5463.12368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794459/
https://www.ncbi.nlm.nih.gov/pubmed/29435416
http://dx.doi.org/10.1002/2211-5463.12368

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