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Antidiabetic Drug Metformin Protects Neuronal Cells against Quinolinic Acid-Induced Excitotoxicity by Decreasing Intracellular Calcium

The antidiabetic drug metformin has been found to have beneficial effects in various neurological disorders; however, the molecular mechanisms underlying these effects remain unclear. Here we report that metformin protects neuronal cells from quinolinic acid (QUIN)-induced excitotoxicity. For this,...

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Detalles Bibliográficos
Autores principales: Jang, Sujeong, Park, Sah-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794475/
https://www.ncbi.nlm.nih.gov/pubmed/29399562
http://dx.doi.org/10.4068/cmj.2018.54.1.24