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A novel HER2 gene body enhancer contributes to HER2 expression

The transcriptional regulation of the human epidermal growth factor receptor-2 (HER2) contributes to an enhanced HER2 expression in HER2-positive breast cancers with HER2 gene amplification and HER2-low or HER2-negative breast cancers following radiotherapy or endocrine therapy, and this drives tumo...

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Detalles Bibliográficos
Autores principales: Liu, Q, Kulak, M V, Borcherding, N, Maina, P K, Zhang, W, Weigel, R J, Qi, H H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794618/
https://www.ncbi.nlm.nih.gov/pubmed/29035388
http://dx.doi.org/10.1038/onc.2017.382