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Novel rare variations in genes that regulate developmental change in N-methyl-d-aspartate receptor in patients with schizophrenia

The mechanism underlying the vulnerability to developing schizophrenia (SCZ) during adolescence remains elusive. Hypofunction of N-methyl-d-aspartate receptors (NMDARs) has been implicated in the pathophysiology of SCZ. During development, the composition of synaptic NMDARs dramatically changes from...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Akane, Nishimura, Fumichika, Inai, Aya, Eriguchi, Yosuke, Nishioka, Masaki, Takaya, Atsuhiko, Tochigi, Mamoru, Kawamura, Yoshiya, Umekage, Tadashi, Kato, Kayoko, Sasaki, Tsukasa, Kasai, Kiyoto, Kakiuchi, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794673/
https://www.ncbi.nlm.nih.gov/pubmed/29423241
http://dx.doi.org/10.1038/hgv.2017.56