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Therapeutic effects of anti-CD154 antibody in cynomolgus monkeys with advanced rheumatoid arthritis

Rheumatoid arthritis is one major chronic inflammatory systemic autoimmune disease. The CD154-CD40 interactions play a critical role in the regulation of immune responses and the maintenance of autoimmunity. Therefore, we aimed to determine whether anti-CD154 antibody treatment show positive effects...

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Detalles Bibliográficos
Autores principales: Choi, Eun Wha, Lee, Kyo Won, Park, Hyojun, Kim, Hwajung, Lee, Jong Hyun, Song, Ji Woo, Yang, Jehoon, Kwon, Yeongbeen, Kim, Tae Min, Park, Jae Berm, Kim, Sungjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794761/
https://www.ncbi.nlm.nih.gov/pubmed/29391506
http://dx.doi.org/10.1038/s41598-018-20566-z