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Therapeutic effects of anti-CD154 antibody in cynomolgus monkeys with advanced rheumatoid arthritis
Rheumatoid arthritis is one major chronic inflammatory systemic autoimmune disease. The CD154-CD40 interactions play a critical role in the regulation of immune responses and the maintenance of autoimmunity. Therefore, we aimed to determine whether anti-CD154 antibody treatment show positive effects...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794761/ https://www.ncbi.nlm.nih.gov/pubmed/29391506 http://dx.doi.org/10.1038/s41598-018-20566-z |