The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation

Recent studies have revealed that newly emerging RasV12-transformed cells are often apically extruded from the epithelial layer. During this cancer preventive process, cytoskeletal proteins plectin and Epithelial Protein Lost In Neoplasm (EPLIN) are accumulated in RasV12 cells that are surrounded by...

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Detalles Bibliográficos
Autores principales: Kasai, Nobuhiro, Kadeer, Ailijiang, Kajita, Mihoko, Saitoh, Sayaka, Ishikawa, Susumu, Maruyama, Takeshi, Fujita, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794774/
https://www.ncbi.nlm.nih.gov/pubmed/29391412
http://dx.doi.org/10.1038/s41598-018-20146-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794774/
https://www.ncbi.nlm.nih.gov/pubmed/29391412
http://dx.doi.org/10.1038/s41598-018-20146-1

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