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ATP-dependent conformational change in ABC-ATPase RecF serves as a switch in DNA repair

RecF is a principal member of the RecF pathway. It interacts with RecO and RecR to initiate homologous recombination by loading RecA recombinases on single-stranded DNA and displacing single-stranded DNA-binding proteins. As an ATP-binding cassette ATPase, RecF exhibits ATP-dependent dimerization an...

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Detalles Bibliográficos
Autores principales: Tang, Qun, Liu, Yan-Ping, Shan, Hai-Huan, Tian, Li-Fei, Zhang, Jie-Zhong, Yan, Xiao-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794780/
https://www.ncbi.nlm.nih.gov/pubmed/29391496
http://dx.doi.org/10.1038/s41598-018-20557-0