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Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages of the disease repair in the form of remyelination often fails, which leads to axonal degeneration and neurological disability. For the rege...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794790/ https://www.ncbi.nlm.nih.gov/pubmed/29391408 http://dx.doi.org/10.1038/s41598-018-19934-6 |