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Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination

Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages of the disease repair in the form of remyelination often fails, which leads to axonal degeneration and neurological disability. For the rege...

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Detalles Bibliográficos
Autores principales: Lentferink, Dennis H., Jongsma, Jacomien M., Werkman, Inge, Baron, Wia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794790/
https://www.ncbi.nlm.nih.gov/pubmed/29391408
http://dx.doi.org/10.1038/s41598-018-19934-6