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Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals

BACKGROUND AND OBJECTIVES: Maximum plasma concentration of biopharmaceuticals sometimes occurs long after completion of intravenous infusion. The objective of this research was to study the hypothetical adsorption of biopharmaceuticals to endothelium and infusion material, which may theoretically ex...

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Detalles Bibliográficos
Autores principales: Reijers, Joannes A. A., Dane, Martijn J. C., van Zonneveld, Anton Jan, Burggraaf, Jacobus, Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794845/
https://www.ncbi.nlm.nih.gov/pubmed/28795390
http://dx.doi.org/10.1007/s13318-017-0430-1